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Neuroimmunology and multiple sclerosis

The Department of Neuroimmunology and MS Research (nims) at the Neurology Clinic combines one of the largest MS clinics in Switzerland with several research groups that pursue clinical, translational and basic research in MS and neuroimmunology. We served not only the wider area of Zürich, but offer second opinion and special treatment options also to patients from entire Switzerland and internationally. A team of experts including specialized nurses and laboratory technicians, physicians and neuropsychologists aim to provide patient care according to highest international standards. This includes counseling in all aspects of MS, comprehensive diagnosis, symptomatic- and immunomodulatory treatments with all approved und available treatments from first-line drugs such as interferon-b, glatiramer-acetate and fingolimod to second line treatments with natalizumab or other already accessible treatment options to cell therapies in severe cases such as autologous hematopoietic stem cell transplantation.

The focus of our research is to understand better the disease heterogeneity of MS using imaging techniques (MRI and optical coherence tomography, OCT), biological markers and motor function. In the laboratory we examine disease mechanisms of MS with particular focus on cellular immunology and biochemistry. Developing new treatments particularly in areas of unmet medical needs of MS such as neuroprotection, induction of tolerance and in the future hopefully also regenerative therapies are another strong interest. The recently approved Clinical Research Focus in MS (KFSPMS) will bring together expertise from scientists and clinicians at other Departments of the University Hospital Zürich (USZ), but also from several research groups at the University Zürich (UZ) and the Federal Institute of Technology (ETH) Zürich. Its aim is to deepen our research in the above areas, but particularly translate knowledge to new treatments as rapidly as possible.

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