Vestibulo-oculomotor laboratory

​Introduction

The Vestibulo-Oculomotor Laboratory at University Hospital Zurich conducts research on the neural systems controlling balance, eye, head, and reaching movements. We are particularly interested in the diagnosis and treatment of central and peripheral diseases of the ocular motor and vestibular systems in humans. Recently, we started to investigate the ocular motor system in zebrafish larvae with the focus on the pathophysiology and treatment of congenital nystagmus. Our laboratory is equipped with unique devices (such as the 3D turntable or the hexapod) that allow us to precisely control and measure human movements in order to study the sensorimotor interactions that are necessary to help us move in dynamic environments.

Major projects

Ocular motor plasticy following vestibular tone asymmetry in humans
Hegemann Stefan et al.
SNF: http://p3.snf.ch/project-122535

Three-dimensional kinematical analysis of ocular motor disorders in humans
Dominik Straumann et al.
SNF: http://p3.snf.ch/project-133125

Study of infantile nystagmus syndrome: development of the ocular motor system, disease mechanism and clinical applications (Marie Heim-Voegtlin grant)
Melody Ying-Yu Huang
SNF: http://p3.snf.ch/project-139754

Pathophysiology of rebound: Instability of cerebellar null representation for ocular motor control and gravity perception
Sarah Marti et al.
SNF: http://p3.snf.ch/project-130163

Using zebrafish mutant belladonna and hypopigmented mice as disease models to study congenital nystagmus in human patients

Dominik Straumann et al.
ZIHP: http://www.zihp.uzh.ch/research/cooperative-projects/current.html